After receiving her medical degree from Beijing Capital Medical University in 1983, Jingjing took a position as a research assistant professor at the Navy General Hospital in Beijing. Then from 1989 to 2000 she worked in the Immunogenetics Laboratory at the Beijing Institute of Pediatrics and contributed to projects including the WHO DIAMOND Project, an IDDM molecular epidemiology in China, a study of CETP gene mutation in four Chinese populations and an HLA disease association study. After that, she worked for a year as a visiting scholar in the Genetic Epidemiology Unit at the National Public Health Institute in Helsinki, Finland where she studied HLA haplotypes of IDDM patients in different populations. In late 2001 she arrived at the University of Chicago and worked for the next 15 years in the Department of Neurosurgery, where she contributed to many different projects probing immunological and neurological systems in mouse and human models. Finally, in 2017, she joined the Esser-Kahn lab, where she assists with our immunoengineering studies in mice.
Beijing Capital Medical University; Beijing P.R. China; 1983
Immunology, molecular biology, animal experiments
Pathogen-like Nano-assemblies of Covalently Linked TLR Agonists Enhance CD8 and NK Cell Mediated Anti-Tumor Immunity.
Saikat Manna, Sampa Maiti, Jingjing Shen, Wenjun Du, Aaron P. Esser-Kahn. ACS Cent. Sci. 2020, 6, 11, 2071–2078. Oct 27, 2020. doi: 10.1021/acscentsci.0c01001
Sampa Maiti, Saikat Manna, Jingjing Shen, Aaron P. Esser-Kahn, and Wenjun Du. Mitigation of Hydrophobicity-Induced Immunotoxicity by Sugar Poly(orthoesters). Journal of the American Chemical Society. 2019.
Saikat Manna, William J. Howitz, Nathan J. Oldenhuis, Alexander C. Eldredge, Jingjing Shen, Fnu Naorem Nihesh, Melissa B. Lodoen, Zhibin Guan , and Aaron P. Esser-Kahn. Immunomodulation of the NLRP3 Inflammasome through Structure-Based Activator Design and Functional. ACS Central Science. 2018. Vol. 4 (8), Pg. 982-995.
Quantitative susceptibility mapping as a monitoring biomarker in cerebral cavernous malformations wi
Hussein A. Zeineddine, MD, Romuald Girard, PhD, Ying Cao, MS, Nicholas Hobson, MS, Maged D. Fam, MD, Agnieszka Stadnik, MS, Huan Tan, PhD, Jingjing Shen, MD, Kiranj Chaudagar, PhD, Robert Shenkar, PhD, Richard E. Thompson, PhD, Nichol McBee, MPH, Daniel Hanley, MD, Timothy Carroll, PhD, Gregory A. Christoforidis, MD and Issam A. Awad, MD. Quantitative susceptibility mapping as a monitoring biomarker in cerebral cavernous malformations wi. Journal of Magnetic Resonance Imaging. 2017.
Measuring Surgical Outcomes in Subaxial Degenerative Cervical Spine Disease Patients: Minimum Clinic
Brenda Auffinger, Sandi Lam, Jingjing Shen, Ben Z. Roitberg. Measuring Surgical Outcomes in Subaxial Degenerative Cervical Spine Disease Patients: Minimum Clinic. Neurosurgery. 2014. Vol. 74, Pg. 206-214.
Usefulness of minimum clinically important difference for assessing patients with subaxial degenerat
Brenda Auffinger, Sandi Lam, Jingjing Shen, Bart Thaci, Ben Z. Roitberg. Usefulness of minimum clinically important difference for assessing patients with subaxial degenerat. Acta Neurochirurgica. 2013. Vol. 155, Pg. 2345–2355.
The Impact of Obesity on Surgeon Ratings and Patient-Reported Outcome Measures After Degenerative Ce
Brenda Auffinger, Sandi Lam. Jennifer Kraninger, Jingjing Shen, Ben Z. Roitberg. The Impact of Obesity on Surgeon Ratings and Patient-Reported Outcome Measures After Degenerative Ce. World Neurosurgery. 2013. Vol. 82, Pg. 345-352.
Comparison between patient and surgeon perception of degenerative spine disease outcomes—a prospecti
Ben Z. Roitberg, Bart Thaci, Brenda Auffinger, Laura Kaplan, Jingjing Shen, Frederick D. Brown, Sandi Lam. Comparison between patient and surgeon perception of degenerative spine disease outcomes—a prospecti. Acta Neurochirurgica. 2013. Vol. 155, Pg. 757-764.
Ethnic and geographical differences in HLA associations with the outcome of hepatitis C virus infect
Jane H Wang, Xin Zheng, Xiaogang Ke, M Tevfik Dorak, Jingjing Shen, Basmattee Boodram, Maurice O'Gorman, Kenneth Beaman, Scott J Cotler, Ronald Hershow and Lijun Rong. Ethnic and geographical differences in HLA associations with the outcome of hepatitis C virus infect. Virology Journal. 2009. Vol. 6.
Shen Jingjing, Yang Ze, Tang Lei, Sun Yiping.. The role of HLA-DRB1*07 and Cw*0602 in development of psoriasis in Chinese patients.. Journal of Clinical Dermatology. 2001. Vol. 30, Pg. 103-116.