Brittany was born and raised in Indiana. Her amazing high school teachers inspired her to study chemistry at Purdue University in West Lafayette, Indiana. There, to escape the long winters, Brittany stayed inside and conducted research in atmospheric chemistry with Professor Paul Shepson. After she graduated in 2012, she worked with Professor Mikhail Shapiro designing gene circuits to probe neuronal function. An NSF Graduate Research Fellow (2015-2020), Brittany is now studying the innate immune system on the single-cell level through a variety of light-based tools.
Brittany's scientific hero is Percy Julian. Her favorite chemistry joke: What do you call an acid with an attitude? A-mean-o-acid.
Brittany's research includes immune programming, protein engineering, chemical biology, and biomaterials.
Small Molecule NF-κB Inhibitors as Immune Potentiators for Enhancement of Vaccine Adjuvants
Brittany A. Moser, Yoseline Escalante-Buendia, Rachel C. Steinhardt, Matthew G. Rosenberger, Britteny J. Cassaidy, Nihesh Naorem, Alfred C. Chon, Minh H. Nguyen, Ngoctran T. Tran, and Aaron P. Esser-Kahn. Front Immunol. 2020; 11: 511513. doi: 10.3389/fimmu.2020.511513
Increased Vaccine Tolerability and Protection via NF-κB Modulation
B. A. Moser, R. C. Steinhardt, Y. Escalante-Buendia, D. A. Boltz, K. M. Barker, B. J. Cassaidy, M.G. Rosenberger, S. Yoo, B. G. McGonnigal, and A. P. Esser-Kahn. Science Advances 09 Sep 2020: Vol. 6, no. 37, eaaz8700. doi: 10.1126/sciadv.aaz8700
A Photoactivatable Innate Immune Receptor for Optogenetic Inflammation
Brittany Moser and Aaron Esser-Kahn. A Photoactivatable Innate Immune Receptor for Optogenetic Inflammation. ACS Chemical Biology. 2017. Vol. 12, Pg. 347-350.
Surface Coating of Nanoparticles Reduces Background Inflammatory Activity while Increasing Particle
Brittany Moser, Rachel Steinhardt, and Aaron Esser-Kahn. Surface Coating of Nanoparticles Reduces Background Inflammatory Activity while Increasing Particle. ACS Biomaterials. 2017. Vol. 3, Pg. 206-213.
Immune potentiator for increased safety and improved protection of vaccines by NF-kB modulation
Brittany A Moser, Rachel C Steinhardt, Yoseline Escalante-Buendia, David A Bolt, Kaylynn M Barker, Stan Yoo, Bethany G McGonnigal, Aaron P Esser-Kahn. Immune potentiator for increased safety and improved protection of vaccines by NF-kB modulation. bioRxiv.
Applications of Immunomodulatory Immune Synergies to Adjuvant Discovery and Vaccine Development
Janine K. Tom, Tyler J. Albin, Saikat Manna, Brittany A. Moser, Rachel C. Steinhardt, Aaron P. Esser-Kahn. Applications of Immunomodulatory Immune Synergies to Adjuvant Discovery and Vaccine Development. Trends in Biotechnology.
Photothermal Nanoparticle Initiation Enables Radical Polymerization and Yields Unique, Uniform Micro
Rachel Steinhardt, Timothy Steeves, Brooke Wallace, Brittany Moser, Dmitry Fishman, and Aaron Esser-Kahn. Photothermal Nanoparticle Initiation Enables Radical Polymerization and Yields Unique, Uniform Micro. ACS Applied Materials & Interfaces.