Fabian was born in Linköping, Sweden, and received his MEng in chemical engineering in 2018 from University College London in the United Kingdom. He wrote his master’s thesis under the supervision of Dr. Ozgur Yazaydin investigating the adsorption of drugs from water using metal-organic frameworks through molecular simulations. In the fall of 2018, he joined the Pritzker School of Molecular Engineering at the University of Chicago to pursue his PhD, co-advised by Professors Juan de Pablo and Rama Ranganathan. In his spare time, he enjoys running, hockey, and spending time outdoors.
Fabian’s research entails using molecular simulations to characterize the local and collective mechanics of proteins which provide a connection between allostery and global coevolution. Through these simulations, he aims to investigate the elastic dynamical motion of the pathway connecting the binding site to allosteric site, providing information that is currently intractable experimentally, and to develop simulation methods to achieve this goal.
Modeling the Binding Mechanism of Remdesivir, Favilavir, and Ribavirin to SARS-CoV-2 RNA-Dependent RNA Polymerase
Byléhn, F., Menéndez, C.A., Perez-Lemus, G.R., Alvarado, W. and De Pablo, J.J., 2021. Modeling the binding mechanism of remdesivir, favilavir, and ribavirin to SARS-CoV-2 RNA-dependent RNA polymerase. ACS central science, 7(1), pp.164-174.
Menéndez, C.A., Byléhn, F., Perez-Lemus, G.R., Alvarado, W. and de Pablo, J.J., 2020. Molecular characterization of ebselen binding activity to SARS-CoV-2 main protease. Science Advances, 6(37), p.eabd0345.