Faculty

Matthew Tirrell

  • Dean of the Pritzker School of Molecular Engineering, the Robert A. Millikan Distinguished Service Professor
  • Research and Scholarly Interests: Biomolecular Engineering, Nanotechnology, Polymer Properties
  • Websites: Tirrell Lab
  • Contact: mtirrell@uchicago.edu
    773.834.2001
  • Assistant: LaKesha Lloyd
  • Office Location:
    Eckhardt Research Center
    Room 299C
    5640 South Ellis Avenue
    Chicago, IL 60637

Matthew Tirrell is the dean of the Pritzker School of Molecular Engineering (PME) and the Robert A. Millikan Distinguished Service Professor at the University of Chicago. His personal research specializes in the manipulation and measurement of polymer surface properties. Dean Tirrell’s work has provided new insight into phenomena such as adhesion, friction, and biocompatibility, and contributed to the development of new materials based on self-assembly of synthetic and bio-inspired materials.

Before becoming dean of Pritzker Molecular Engineering in 2011, Tirrell served as the Arnold and Barbara Silverman Professor and chair of the Department of Bioengineering at the University of California, Berkeley, and as professor of materials science and engineering and chemical engineering and faculty scientist at Lawrence Berkeley National Laboratory. Prior to that, he was dean of engineering at the University of California, Santa Barbara for 10 years. Tirrell began his academic career at the University of Minnesota as an assistant professor in the Department of Chemical and Materials Engineering and later became head of the department. Tirrell also served as Deputy Laboratory Director for Science at Argonne National Laboratory, where he was responsible for integrating the laboratory’s research and development efforts and science and technology capabilities. 

Tirrell received his BS in chemical engineering from Northwestern University and his PhD in polymer science and engineering from the University of Massachusetts. He has received many honors, including the Polymer Physics Prize of the American Physical Society and election to the National Academy of Sciences, National Academy of Engineering, and the American Academy of Arts and Sciences.

Matthew Tirrell is a pioneering researcher in the fields of biomolecular engineering and nanotechnology, specializing in the manipulation and measurement of the surface properties of polymers, materials that consist of long, flexible chain molecules. His work combines microscopic measurements of intermolecular forces with the creation of new structures. His work has provided new insight into polymer properties, especially surface phenomena, such as adhesion, friction, and biocompatibility, and new materials based on self-assembly of synthetic and bioinspired materials.

Spatiotemporal Formation and Growth Kinetics of Polyelectrolyte Complex Micelles with Millisecond Resolution
Wu, Hao, Jeffrey M. Ting, Boyuan Yu, Nicholas E. Jackson, Siqi Meng, Juan J. de Pablo, and Matthew V. Tirrell. "Spatiotemporal Formation and Growth Kinetics of Polyelectrolyte Complex Micelles with Millisecond Resolution." ACS Macro Letters 9, no. 11 (2020): 1674-1680.

Impact of wet-dry cycling on the phase behavior and compartmentalization properties of complex coacervates
Fares, Hadi M., Alexander E. Marras, Jeffrey M. Ting, Matthew V. Tirrell, and Christine D. Keating. "Impact of Wet-Dry Cycling on the Phase Behavior and Compartmentalization Properties of Complex Coacervates." (2020).

Probing Diffuse Polymer Brush Interfaces Using Resonant Soft X-ray Scattering
De Hoe, Guilhem X., Jun Mao, Zhang Jiang, Seth B. Darling, Matthew V. Tirrell, and Wei Chen. "Probing Diffuse Polymer Brush Interfaces Using Resonant Soft X-ray Scattering." Synchrotron Radiation News 33, no. 4 (2020): 24-30.

Structure, Morphology, and Rheology of Polyelectrolyte Complex Hydrogels Formed by Self-Assembly of Oppositely Charged Triblock Polyelectrolytes
Srivastava, Samanvaya, Adam E. Levi, David J. Goldfeld, and Matthew V. Tirrell. "Structure, morphology, and rheology of polyelectrolyte complex hydrogels formed by self-assembly of oppositely charged triblock polyelectrolytes." Macromolecules 53, no. 14 (2020): 5763-5774. Harvard

Comparing Zwitterionic and PEG Exteriors of Polyelectrolyte Complex Micelles
Ting, Jeffrey M., Alexander E. Marras, Joseph D. Mitchell, Trinity R. Campagna, and Matthew V. Tirrell. "Comparing Zwitterionic and PEG Exteriors of Polyelectrolyte Complex Micelles." Molecules 25, no. 11 (2020): 2553.

Effect of mixed solvents on polyelectrolyte complexes with salt
Meng, S., Liu, Y., Yeo, J., Ting, J. M., & Tirrell, M. V. Effect of mixed solvents on polyelectrolyte complexes with salt. Colloid and Polymer Science, 1-8.

An in situ shearing x-ray measurement system for exploring structures and dynamics at the solid–liquid interface
Qiao, Yijun, Hua Zhou, Zhang Jiang, Qiming He, Shenglong Gan, Hongdong Wang, Shizhu Wen et al. "An in situ shearing x-ray measurement system for exploring structures and dynamics at the solid–liquid interface." Review of Scientific Instruments 91, no. 1 (2020): 013908. Harvard

Assembly and Characterization of Polyelectrolyte Complex Micelles
Marras, A. E., Vieregg, J. R., Tirrell, M. V. Assembly and Characterization of Polyelectrolyte Complex Micelles. J. Vis. Exp. (157), e60894, doi:10.3791/60894 (2020).

Mechanism of Dissociation Kinetics in Polyelectrolyte Complex Micelles
Wu, Hao, Jeffrey M. Ting, and Matthew V. Tirrell. "Mechanism of Dissociation Kinetics in Polyelectrolyte Complex Micelles." Macromolecules (2019).

Hydrophobically assembled nanoparticles: Self-assembled nanoparticles
Wang, J., Mellas, M., Tirrell, M. and Chung, E.J., 2020. Hydrophobically assembled nanoparticles: Self-assembled nanoparticles. In Nanoparticles for Biomedical Applications (pp. 325-347). Elsevier.

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