Building Microvasculature for Regeneration and Disease Modeling

The microvasculature is a critical system that influences tissue environments, impacting both health and disease and is essential for the proper function of all tissues. Therefore, an accurate microvascular structure and function are crucial for engineered tissue regeneration and disease modeling. In this seminar, she will present her efforts to create perfusable microvascular models. These models allow for precise control over vascular geometry, cellular composition, hemodynamics, and extracellular matrices. She will also highlight how she use these models to study vascular inflammation, understand disease onset and progression, and test new drugs. With spatiotemporal control, these microvascular models provide a means to model vascular injury, tissue regeneration, and therapeutic development.